Huihui is a graduate of the Department of Fine Arts at National Taiwan Normal University and the Experimental Animation Program at CalArts. She has staged multiple solo exhibitions of her work in Taipei, and was a featured artist in the Taiwan Pavilion at the Angoulême International Comics Festival. Following the publishing of her first graphic novel, Blowing-Up Adventure of Me!, Huihui collaborated with playwright Chien Li-Ying to recast her script Tender Is the Night as a graphic novel. The Reporter Files 3: Low-Temp Relationships published in 2024, is her most recent work.